NEET (UG) · Zoology, Class 12
Human Reproduction: NEET PYQ, 2018–2026
Human Reproduction (Zoology, Class 12) has been asked 27 times in the 7 NEET papers from 2018, 2020, 2021, 2023, 2024, 2025 and 2026: about 3.9 questions a paper, 9% of all Zoology questions. It is the 2nd most-asked of 15 Zoology chapters. NEET 2026 had 5 from it. Last checked 28 October 2026.
Questions per paper
Year by year.
| Year | Questions |
|---|---|
| 2018 | 4 |
| 2020 | 3 |
| 2021 | 3 |
| 2023 | 3 |
| 2024 | 4 |
| 2025 | 5 |
| 2026 | 5 |
From 2021 to 2024 each paper had 200 questions (a Section B with a choice); the others had 180.
Inside the chapter
Topics asked most.
- Embryonic development9
- Gametogenesis7
- Menstrual cycle6
- Male and female reproductive systems5
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10 Human Reproduction questions to practise.
Our own questions, written in the NEET pattern and checked, each with an explanation. Pick an option to see the answer.
Q1 · Zoology · Human Reproduction
Which hormone surge in the middle of the menstrual cycle triggers ovulation in humans?
Answer: (B)
Principle: ovulation is triggered by a sharp midcycle surge of LH from the anterior pituitary. Rising oestrogen from the maturing follicle feeds back positively on the pituitary to produce this surge. The LH surge causes the Graafian follicle to rupture, releasing the secondary oocyte. Hence the LH surge is the correct answer.
Q2 · Zoology · Human Reproduction
During the luteal (secretory) phase of the ovarian cycle, which hormone secreted by the corpus luteum is mainly responsible for maintaining the thickened, glandular endometrium?
Answer: (A)
The corpus luteum forms from the ruptured follicle after ovulation and secretes progesterone along with some oestrogen. Progesterone converts the endometrium into a secretory, glandular tissue. Remember that LH maintains the corpus luteum and progesterone acts on the uterus.
Q3 · Zoology · Human Reproduction
Which of the following statements about the hormones of human pregnancy is correct?
Answer: (D)
The placenta produces hCG, hPL, estrogens and progestogens, and in the later phase of pregnancy the ovary also secretes relaxin. hCG, hPL and relaxin are produced in women only during pregnancy. In addition, the levels of estrogens, progestogens, cortisol, prolactin and thyroxine increase severalfold in the maternal blood, which supports foetal growth and the maintenance of pregnancy.
Q4 · Zoology · Human Reproduction
Which hormone, released from the posterior pituitary, acts with the foetal ejection reflex to stimulate the uterine contractions that expel the foetus at parturition?
Answer: (A)
Principle: at the end of pregnancy, the foetus and placenta release signals that bring about parturition. The foetal ejection reflex causes the release of oxytocin from the posterior pituitary. Oxytocin stimulates stronger uterine contractions, which push the foetus out, and this creates a positive feedback loop. Applying this: the hormone from the posterior pituitary that drives expulsion is oxytocin.
Q5 · Zoology · Human Reproduction
The first trimester of human pregnancy, roughly the first twelve weeks, is the period in which most major organs of the foetus are laid down. Which term describes this process?
Answer: (A)
Embryonic development in humans has three phases: cleavage and implantation in the first week, gastrulation and early organ formation in the following weeks, and then organogenesis, which forms the rudiments of organs during the first trimester. In the second and third trimesters the foetus mainly grows and matures. Identify the process by what it produces: organs, which is organogenesis.
Q6 · Zoology · Human Reproduction
During spermiogenesis, the acrosome is formed from vesicles derived from which organelle, and what is its functional role at fertilisation?
Answer: (A)
Principle: spermiogenesis converts a round spermatid into a spermatozoon with three regions. The Golgi apparatus forms the acrosomal vesicle, which spreads over the anterior part of the nucleus to form the acrosome. The acrosome contains enzymes that enable penetration of the egg's protective layers. Mitochondria form the middle piece, and centrioles contribute to the tail. Only the Golgi-origin option matches all of these facts.
Q7 · Zoology · Human Reproduction
In which region of the testis are the Leydig cells located?
Answer: (B)
Testicular cells have two main locations. The seminiferous tubules contain germ cells and Sertoli cells. Between the tubules is the interstitial tissue, which contains Leydig cells. Leydig cells respond to LH by secreting androgens such as testosterone, which support spermatogenesis and male secondary sexual characters.
Q8 · Zoology · Human Reproduction
Which hormone, secreted by Sertoli cells, provides negative feedback on the anterior pituitary to regulate the secretion of FSH?
Answer: (A)
Principle: the hypothalamic GnRH stimulates the anterior pituitary to release FSH and LH. FSH acts on Sertoli cells, which respond by secreting inhibin. Inhibin then acts back on the anterior pituitary to suppress FSH, which keeps spermatogenesis controlled. Application: the Sertoli-cell hormone in this loop is inhibin.
Q9 · Zoology · Human Reproduction
A human blastocyst implants in the uterus about 7 days after fertilisation. At the time of implantation, which combination correctly describes the endometrium and the hormone chiefly responsible for maintaining it?
Answer: (B)
Principle: the uterine cycle has a proliferative phase (oestrogen-driven repair) and a secretory phase after ovulation (progesterone-driven, preparing the endometrium for implantation). Application: implantation occurs about 7 days after fertilisation, when the endometrium is in the secretory phase. The corpus luteum secretes progesterone to maintain this state. If pregnancy is established, the placenta later takes over progesterone production, but it is not yet the source at implantation.
Q10 · Zoology · Human Reproduction
Which layer of the wall of the uterus shows strong contractions during the delivery of the baby?
Answer: (A)
The wall of the uterus has three layers: the external thin membranous perimetrium, the middle thick layer of smooth muscle called the myometrium, and the inner glandular endometrium. The endometrium changes cyclically during the menstrual cycle, while the myometrium contracts strongly during delivery.
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All 27 real NEET questions from Human Reproduction.
The questions from the actual papers, with the official answer and an explanation for each — chapter by chapter, or as full timed papers.
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About Human Reproduction in NEET.
How many questions come from Human Reproduction in NEET?
Human Reproduction (Zoology, Class 12) has been asked 27 times in the 7 NEET papers from 2018, 2020, 2021, 2023, 2024, 2025 and 2026: about 3.9 questions a paper, 9% of all Zoology questions. It is the 2nd most-asked of 15 Zoology chapters. NEET 2026 had 5 from it.
Which topics of Human Reproduction are asked most in NEET?
Embryonic development (9), Gametogenesis (7), Menstrual cycle (6), Male and female reproductive systems (5), counted over the papers from 2018–2026.
Is Human Reproduction important for NEET 2027?
It is in the syllabus in force, so it can be asked. By past papers it ranks 2 of 15 in Zoology; use that to decide how much time it gets, not whether to study it.
Where can I solve Human Reproduction NEET previous year questions?
On Nikaalle, free: sign up and practise every past NEET question from Human Reproduction with an explanation for each, or sit the full papers timed. The ten questions on this page are our own, written in the same pattern.
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